Invited Faculty
  • John Harley
    Cincinnati Education and Research for Veterans Foundation
  • Dr. Harley has worked to find the origins of lupus for more than three decades. He began with an immunochemical approach that sought to identify the first autoantigenic structures in the development of lupus autoimmunity. These studies nominated Epstein-Barr virus (EBV) and the host humoral response to Epstein Barr Virus nuclear antigen 1 (EBNA1), which was strongly supported by the serologic and viral DNA epidemiology of EBV in pediatric lupus. Recent experiments suggest that anti-EBNA1 antibody is a requirement for developing lupus in >90% of patients. Further, etiologic exposure window data support EBV and the anti-EBNA1 antibody response being an etiology for the pathogenesis of lupus.
    Research & Clinical Focus


    Epstein-Barr virus




  • Date Time Room Session Title Lecture Title
    May 19 17:00-17:20 Room Grand Ballroom 101 [Concurrent Session 8] Omics and Breakthrough Technology Lupus autoimmunity and Epstein-Barr virus informs other idiopathic diseases